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QUESTION ON NOTICE

Question:

227. The virus needs two enzymes to cross the membrane whereas the vaccine needs none as it relies in transfection – is that correct? If that is the case, then is it fair to say the vaccine is more infectious, isn’t it? 286. Aren’t nasal sprays better than vaccines for respiratory viruses that enter through the airways? 287. What steps or tests has the health department taken to ensure that immune imprinting or antibody dependent enhancement is not occurring with repeated booster shots. This is a well-known phenomenon, dengue fever being a prime example. It was highlighted by Pfizer as a potential risk. Furthermore, why isn’t this potential risk highlighted in any Covid booster advertising? 290. Is the overuse of booster and the use of a stronger spike protein causing the immune system to downregulate in other areas leading to cancer and diabetes?

Answer:

Question Number: 269
PDR Number: SQ22-000640
Date Submitted: 21/11/2022
Department or Body: Department of Health

Question 227 The vaccine mRNA encapsulated in lipid nanoparticles (LNPs) enters into cells without the assistance of enzymes. The COVID-19 vaccines are designed to trigger immunity against SARS-CoV-2 virus. The vaccines are not infectious themselves given that the spike proteins expressed following vaccination is not a pathogen. As indicated in answers to other questions, the vaccine mRNA is broken down rapidly after it is released from LNPs and rapidly eliminated from tissues with half-lives of 15-60 ours except for the injection site muscle, lymph nodes and spleen (detectable five days after dosing).

Question 286 There has been extensive research on nasal spray vaccines against respiratory viruses. Nasal spray vaccines against COVID-19 are approved in some countries, particularly developing countries (available at: www.nature.com/articles/d41586-022-02851-0). However, there is no robust clinical data available for assessing their efficacy and safety, and several have not met with success in trials. Therapeutic Goods Administration (TGA) have not received applications for any nasal vaccines against COVID-19. Nasal sprays may refer to a product designed to act as a barrier in the nasal cavity or to a nasally administered vaccine. However, neither are currently registered on the Australian Register of Therapeutic Goods (ARTG) for the prevention of COVID-19.

Question 287 All therapeutic goods are associated with benefits and risks (including COVID-19 vaccines). The benefit-risk balance remains positive for the currently registered COVID-19 vaccines, and the benefits significantly outweigh the potential risks of immune imprinting. Immune imprinting may potentially occur in response to any antigen, including SARS?CoV?2 or influenza virus. This can be in response to natural infection, vaccination, or booster vaccination. For SARS?CoV?2, current evidence indicates that immune imprinting likely only affects the humoral immune response against SARS-CoV-2 variants whilst preserving T and B cell responses, including vaccine/booster-induced cross-reactive responses against SARS-CoV-2 variants. This indicates ongoing protection against SARS-CoV-2 variants, including longer-term protection. Furthermore, this effect may be supported further by vaccines or boosters targeting circulating variants specifically, in particular in the context of a large amount of shared epitopes.

Question 290 There is no evidence of immunosuppression from booster doses of vaccines. There are no reports of immunosuppression from annual booster vaccination with influenza vaccines. There is no clinical evidence that the use of a COVID-19 booster vaccine at any of the recommended doses is causing the immune system to downregulate leading to cancer or diabetes.

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HAVE YOUR SAY

LATEST QUESTIONS ON NOTICE

Senator RENNICK: Okay-last question. I had a conversation with Gavin Morris a couple of years ago about the way the ABC reports the increase in temperature from 1910. The ABC, like many other media organisations, reports the homogenised data without actually explaining the difference between the homogenised data and the raw data. Gavin Morris stressed that they reported the raw data. That is incorrect; the ABC reports the homogenised data. So I’ll ask this question again: why won’t the ABC distinguish between the raw data and the homogenised data, which is a different dataset to the actual observations recorded by the bureau? Mr Anderson: I don’t know the answer to that. I will need to take that on notice and provide a response to you. Senator RENNICK: Okay. I would like to point out that Gavin Morris did say last time that they reported the raw data and that they distinguished between raw and homogenised. I’ll stress this again, the ABC doesn’t, but I think in terms of full transparency they should.

29/11/2022

Senator RENNICK: Do we have any costings for storage? How much will it cost, in terms of storage, to get to our 2030 target? Mr Duggan: A lot of this is, of course, private provisions. In fact, you’d hope that the vast majority of it was. Government has policies that would assist thatSenator RENNICK: That is fine, but we’re told every day that renewables are cheaper. I want that quote substantiated by proper costings, whether it’s funded publicly or privately, because it’s going to end up either out of the taxpayer’s pocket or on their energy bill. So I’m looking for costings just on storage. I want it on other issues as well, such as transmission, but I’m asking: do you have costings on that storage? Ms Brunoro: We’ll take that on notice. The difficulty with answering that question with any kind of precision is that, in terms of deep storage, it will relate to a number of technologies-it’s the same for deep and shallow. It will ultimately depend on the precise mix of those, but we can do things at a high level with respect to the nature of the type of storage that fits within that and provide some estimates to you. Senator RENNICK: So you don’t have definite figures at the moment? Mr Duggan: What we can do for you-and we’ll have to take this on notice-is look at the existing pipeline of projects that are underway and what the private proponents have told us about the cost of those things. We can add to that: through Rewiring the Nation or other policies that are helping to assist that, we can break down the government contribution to that. But we just don’t have all that detail in front of us. Senator RENNICK: I want government and private, because, ultimately, it going to cost the consumer through taxes or energy bills. But is that fair to say that that’s not completed yet? Mr Duggan: We will take that on notice and we’ll endeavour to do our best to come back to you.

28/11/2022

Senator RENNICK: Thanks very much. Yet again, in terms of the overall modelling, have you got a breakout of how many turbines you need, how many solar panels you need to get to 82 per cent renewables? Ms Brunoro: Again, the Integrated System Plan does provide an indication of the type of the level of renewable energy, so just bear with us a second. Mr Peisley: Sorry, I don’t think we do have that figure in front of us. We’re happy to take it on notice and get it to you. Ms Brunoro: But if it gives you a sense of it, it’s nine times the amount of the existing variable renewable energy that currently is-well, as of when the last Integrated System Plan came out, it was operating in the NEM at that point. So that gives you the quantum ofSenator RENNICK: So nine times what? Ms Brunoro: Nine times. Senator RENNICK: Yes, but what? Ms Brunoro: The variable renewable energy that is currently in the National Electricity Market. Senator RENNICK: So what’s the cost of that? Ms Brunoro: Again, Senator, it depends on the mix of technologies that you’re going to deploy. There are some figures that we can pull out for you around what they roughly think around different-solar versus wind for instance. We can actually seek to provideSenator RENNICK: So can you give me some definite costings on that? Not now, but on notice?

28/11/2022

1. According to the December 2020 update, Australia emitted 499 million tonnes of carbon dioxide equivalent to a 5 per cent decrease on 2019. Australia’s grasslands are estimated to be 440 million hectares and native forest 147 million hectares, a total of approximately 587 hectares. It is estimated forest and grasslands absorb between 0.5 and 2 tonnes of carbon per hectare. Assuming an average of 1 tonne of CO2 absorbed by these landscapes then isn’t Australia already at net zero? 2. Can the CSIRO provide a comprehensive roadmap of the work required for Australia to meet a 43% reduction in CO2 by 2030? This roadmap should set out the length of transmission lines, the number of transmission towers, the number of solar panels (for a given wattage), the number of wind turbines (for a given wattage), the number of batteries (for a given storage), the amount of lithium, copper, cobalt, nickel, concrete, and steel etc. needed to build the aforesaid generators and storage. It will need to include the amount of land needed for solar, wind, transmission, and storage products and the biodiversity offsets. Could the amount of CO2 required to build, recycle, or dispose of the aforementioned items also be included. Likewise, could the cost of building, recycling, and disposing of the aforementioned items also be clearly outlined. Biodiversity impacts such as increased tyre wear due to heavier batteries in cars, increased breaking distance on roadkill, impact on bats and birds from transmission lines and wind turbines, and removal of native flora and fauna due to land use should also be clearly outlined. 3. If the CSIRO cannot provide, can it state which department is responsible for maintaining and tracking the roadmap and refer the question onto them? 4. Could the change in Earth’s temperature as a result of Australia undertaking the 43% reduction in CO2 measures please be stated in order to ensure appropriate benchmarking and accountability if targets are not met? 5. Could the CSIRO confirm if every country uses the same methods to calculate CO2 emission and reductions? If not, why not? What guarantees are there under the Net Zero that Australia won’t be disadvantaged as a result of signing up to the Net Zero pledge?

23/11/2022

1. Can the Department of Climate Change, Energy, the Environment and Water provide a comprehensive roadmap of the work required for Australia to meet a 43% reduction in CO2 by 2030. This roadmap should set out the length of transmission lines, the number of transmission towers, the number of solar panels (for a give wattage), the number of wind turbines (for a given wattage), the number of batteries (for a given storage), the amount of lithium, copper, cobalt, nickel, concrete, and steel etc. needed to build the aforesaid generators and storage. It will need to include the amount of land needed for solar, wind, transmission and storage products, and the biodiversity offsets. Could the amount of CO2 required to build, recycle, or dispose of the aforementioned items also be included? Likewise, could the cost of building, recycling, and disposing of the aforementioned items also be clearly outlined? Biodiversity impacts such as increased tyre wear due to heavier batteries in cars, increased breaking distance on roadkill, impact on bats and birds from transmission lines and wind turbines, and removal of native flora and fauna due to land use should also be clearly outlined. 2. If the Department cannot provide, can it state which department is responsible for maintaining and tracking the roadmap and refer the question onto them?

21/11/2022

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