Question Number: 313
PDR Number: SQ22-000689
Date Submitted: 21/11/2022
Department or Body: Department of Health
The spike protein in the mRNA vaccine has a transmembrane anchor region that makes the protein attach to the cell membrane and, in the absence of a signal sequence for secretion, will not be secreted or released into the blood stream from the cells (available at: www.pubmed.ncbi.nlm.nih.gov/33117378 and https://pubmed.ncbi.nlm.nih.gov/34400651/). Therefore, while the presence of spike proteins at very, very low levels cannot be excluded, as per Professor Skerritts comments, if there are trace levels of any spike proteins there is no evidence of any harm to the human body. Nonclinical animal toxicity studies, conducted at very high vaccine doses, and human data demonstrated the safety of the provisionally approved mRNA vaccines.